TY - JOUR ID - 8961 TI - Synthesis and characterization of CdO/GrO nanolayer for in vivo imaging JO - Nanomedicine Journal JA - NMJ LA - en SN - 2322-3049 AU - Pardakhty, Abbas AU - Foroughi, Mohammad Mehdi AU - Ranjbar, Mehdi AD - Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran AD - Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran AD - Young Researchers and Elite Club, Kerman Branch, Islamic Azad University, Kerman, Iran Y1 - 2017 PY - 2017 VL - 4 IS - 3 SP - 191 EP - 196 KW - CdO/GrO KW - Hexagonal nanostructures KW - In vivo targeting KW - Optical investigation DO - 10.22038/nmj.2017.8961 N2 - Objective(s): Nanomaterials are playing major roles in imaging by delivering large imaging payloads, yielding improved sensitivity. Nanoparticles have enabled significant advances in pre-clinical cancer research as drug delivery vectors. Inorganic nanoparticles such as CdO/GrO nanoparticles have novel optical properties that can be used to optimize the signal-to-background ratio. This paper reports on a novel processing route for preparation of CdO/GrO nanolayer and investigation of its optical properties for application in in vivo targeting and imaging.Materials and Methods: Nanostructures were synthesized by reacting cadmium acetate and graphene powder. The effects ofdifferent parameters such as power and time of irradiation were also studied. Finally, the efficiency of CdO/GrO nanostructures as an optical composite was investigated using photoluminescence spectrum irradiation. CdO/GrO nanostructures were characterized by means of X-ray diffraction (XRD), atomic force microscopy (AFM), scanning electron microscopy (SEM), Fourier transform infrared (FT-IR) and photoluminescence (PL) spectroscopy.Results: According to SEM images, it was found that sublimation temperature had significant effect on morphology and layers. The spectrum shows an emission peak at 523 nm, indicating that CdO/GrO nanolayer can be used for in vivo imaging.Conclusion: The estimated optical band gap energy is an accepted value for application in in vivo imaging using a QD–CdO/GrO nanolayer. UR - https://nmj.mums.ac.ir/article_8961.html L1 - https://nmj.mums.ac.ir/article_8961_42e1f1988e03ec34fced013e24518784.pdf ER -