<?xml version="1.0" encoding="utf-8"?>
			<journal>
			<title>Nanomedicine Journal</title>
			<title_fa></title_fa>
			<short_title>Nanomed J</short_title>
			<subject>Medical Sciences</subject>
			<web_url>https://nmj.mums.ac.ir/</web_url>
			<journal_hbi_system_id>0</journal_hbi_system_id>
			<journal_hbi_system_user></journal_hbi_system_user>
			<journal_id_issn>2322-3049</journal_id_issn>
			<journal_id_issn_online>2322-5904</journal_id_issn_online>
			<journal_id_pii></journal_id_pii>
			<journal_id_doi></journal_id_doi>
			<journal_id_iranmedex></journal_id_iranmedex>
			<journal_id_magiran></journal_id_magiran>
			<journal_id_sid></journal_id_sid>
			<journal_id_nlai></journal_id_nlai>
			<journal_id_science></journal_id_science>
			<language>en</language>
			<pubdate>
				<type>jalali</type>
				<year>2023</year>
				<month>7</month>
				<day>1</day>
			</pubdate>
			<pubdate>
				<type>gregorian</type>
				<year>2023</year>
				<month>7</month>
				<day>1</day>
			</pubdate>
			<volume>10</volume>
			<number>3</number>
			<publish_type>online</publish_type>
			<publish_edition>1</publish_edition>
			<article_type>fulltext</article_type>
			<articleset><article>
				<language>en</language>
				<article_id_issn></article_id_issn>
				<article_id_issn_online></article_id_issn_online>
				<article_id_pubmed></article_id_pubmed>
				<article_id_pii></article_id_pii>
				<article_id_doi></article_id_doi>
				<article_id_iranmedex></article_id_iranmedex>
				<article_id_magiran></article_id_magiran>
				<article_id_sid></article_id_sid>
				<title_fa></title_fa>
				<title>Green synthesis of Ag-NPs as a metal nanoparticle and ZnO-NPs as a metal oxide nanoparticle: Evaluation of the in vitrocytotoxicity, anti-oxidant, anti-angiogenic activities</title>
				<subject_fa></subject_fa>
				<subject></subject>
				<content_type_fa>مقاله پژوهشی</content_type_fa>
				<content_type>Research Paper</content_type>
				<abstract_fa><![CDATA[]]></abstract_fa>
				<abstract><![CDATA[Objective(s): The study aimed to synthesize both silver- and zinc-oxide nanoparticles utilizing the Peganum harmala smoke extract (PHSE) bio-platform to evaluate their cytotoxicity on different types of human cancer cell lines and study their anti-oxidant, and anti-angiogenic potentials. Materials and Methods: The Silver (Ag) and zinc oxide (ZnO) nanoparticles (NP) were produced utilizing the green-synthesize method by applying the PHSE bio-platform. After characterization by X-Ray Diffraction (XRD), dynamic light scattering (DLS), Field emission scanning electron microscopy (FESEM), and Fourier-transform infrared spectroscopy (FTIR) methods. MTT assay was used for the evaluation toxicity of nanoparticles. ABTS, DPPH, FRAP, and ROS for anti-oxidant capacity, chicks’ chorioallantoic membrane (CAM), and qPCR for anti-angiogenesis effects of nanoparticles were used. Results: Ag-NPs (82.42 nm) and ZnO-NPs (163.05 nm) inhibited prostate, ovarian, and liver malignant cells. Inhibition of ABTS•+ and DPPH•+ and increasing the rate of intracellular ROS exhibited the anti and pro-oxidant capacity of Ag and ZnO-NPs out and inside of malignant cells. Also, their anti-angiogenesis impact was verified by significant dose-dependent VEGF and VEGFR down-regulation and the decreased blood vessels in the CAM. Conclusion: The anti-oxidant, cytotoxicity and anti-angiogenesis effects of Ag and ZnO-NPs synthesized from Pecan smoke extract make it possible to use these nanoparticles in cancer chemotherapy.]]></abstract>
				<keyword_fa></keyword_fa>
				<keyword>Angiogenesis inhibitors, Anti-Oxidants, Metal Nanoparticles</keyword>
				<start_page>245</start_page>
				<end_page>258</end_page>
				<web_url>https://nmj.mums.ac.ir/article_22428.html</web_url>
			<author_list><author>
				<first_name>Hoda</first_name>
				<middle_name></middle_name>
				<last_name>Shabestarian</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>hodashabestarian@yahoo.com</email>
				<code>97686</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Biochemistry, Faculty of Biological Science, North Tehran Branch, Islamic Azad University, Tehran, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Masoud</first_name>
				<middle_name></middle_name>
				<last_name>Homayouni Tabrizi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>mhomayouni6@gmail.com</email>
				<code>97687</code>
				<coreauthor>Yes</coreauthor>
				<affiliation>Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Monireh</first_name>
				<middle_name></middle_name>
				<last_name>Movahedi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>mon_movahedi@yahoo.com</email>
				<code>97688</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Biochemistry, Faculty of Biological Science, North Tehran Branch, Islamic Azad University, Tehran, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Ali</first_name>
				<middle_name></middle_name>
				<last_name>Neamati</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>neamati.ali@gmail.com</email>
				<code>97689</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Fariba</first_name>
				<middle_name></middle_name>
				<last_name>Sharifnia</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>sharifnia2021@gmail.com</email>
				<code>97690</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Biology, Faculty of Biological Science, North Tehran Branch, Islamic Azad University, Tehran, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author></author_list>
				</article>
			</articleset>
			</journal>