1Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
2Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran
Objective(s): According to the unique properties of magnetic nanoparticles, Nickel Metal-Organic Frameworks (MOF) was synthesized successfully by ultrasound irradiation. Metal-organic frameworks (MOFs) are organic–inorganic hybrid extended networks that are constructed via covalent linkages between metal ions/metal clusters and organic ligands called a linker. Materials and Methods: The nanoparticles were synthesized by Ultrasound Method Under a synthesis conditions, All chemicals were used as received without further purification. Scanning electron microscopy (SEM) images were obtained on LEO- 1455VP equipped with an energy dispersive X-ray spectroscopy at university of Kashan in Iran. Transition electron microscopy (TEM) images were obtained on EM208 Philips transmission electron microscope with an accelerating voltage of 200 kV. Results: Results showed that Ni-MOF synthesized by this method, had smaller particle size distribution and It was found that the different kinds of ligand leads to preparation products with different morphologies and textural properties. Moreover, ultrasound irradiation method has significant effect on microstructures of as-synthesized MOFs and can improve their textural properties compared to method without using hydrothermal route.The XRD patterns of the samples obtained from ultrasound irradiation was well matched with that of as-prepared Ni-MOF by solvothermal method. Conclusion: This rapid method of ultrasonic radiation as compared to the classical solvothermal synthesis, showed promising results in terms of size distribution, surface area, pore diameter and pore volume.
1. Nehra A, Singh KP. Current trends in nanomaterial embedded field effect transistor-based biosensor. Biosens Bioelectron. 2015; 74 (1): 731-743.
2. Chen KI, Li BR, Chen YT. Silicon nanowire field-effect transistor-based biosensors for biomedical diagnosis and cellular recording investigation. Nano Today. 2011; 30 (2): 131-154.
3. Murray AR, Kisin ER, Tkach AV, Yanamala N, Mercer R, Young SH, Fadeel B, Kagan VE, Shvedova AA. Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos. Part Fibre Toxicol. 2012; 9(10): 1-19.
4. Pujalté I, Passagne I, Brouillaud B, Tréguer M, Durand E, Ohayon-Courtès C. Cytotoxicity and oxidative stress induced by different metallic nanoparticles on human kidney cells. Part Fibre Toxicol. 2011; 8(10): 1-16.
5. Jeng HA, Swanson J. Toxicity of metal oxide nanoparticles in mammalian cells. J Environ Sci Health. 2006; 41(12): 2699-2711.
6. Song W, Zhang J, Guo J, Zhang J, Ding F, Li L. Role of the dissolved zinc ion and reactive oxygen species in cytotoxicity of ZnO nanoparticles. Toxicol Lett. 2010; 199(3): 389-397.
7. Boonstra J, Post JA. Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cells. Gene. 2004; 33 (7): 1-13.
8. Zabirnyk O, Yezhelyev M, Seleverstov O. Nanoparticles as a novel class of autophagy activators. Autophagy. 2007; 3(3): 278-281.
9. Yu L, Lu Y, Man N, Yu SH, Wen P. Rare earth oxide nanocrystals induce autophagy in HeLa cells. Small. 2009; 5(24): 2784-2787.
10. Chen Y, Yang L, Feng C, Wen P. Nano neodymium oxide induces massive vacuolization and autophagic cell death in non-small cell lung cancer NCI-H460 cells. Biochem Biophys Res. 2005; 337(1): 52-60.
11. Lanone S, Boczkowski J. Biomedical applications and potential health risks of nanomaterials: molecular mechanisms. Curr Mol Med. 2006; 6(6): 651-663.
12. Zhang H, Shan Y, Dong L. A comparison of TiO2and ZnO nanoparticles as photosensitizers in photodynamic therapy for cancer. J Biomed Nanotechnol. 2014; 10(8): 1450-1457.
13. Goharshadi EK, Abareshi M, Mehrkhah R, Samiee S, Moosavi M, Youssefi A. Preparation, structural characterization, semiconductor and photoluminescent properties of zinc oxide nanoparticles in a phosphoniumbased ionic liquid. Mat Sci Semicon Proc. 2011; 14(1): 69-72.
14. Goharshadi EK, Ding Y, Jorabchi MN, Nancarrow P. Ultrasound-assisted green synthesis of nanocrystalline ZnO in the ionic liquid [hmim][NTf 2]. Ultrason Sonochem. 2009; 16(1): 120-123.
15. Goharshadi EK, Ding Y, Nancarrow P. Green synthesis of ZnO nanoparticles in a room-temperature ionic liquid 1- ethyl-3-methylimidazolium bis (trifluoromethylsulfonyl) imide. J Phys Chem Solids. 2008; 69(8): 2057-2060.
16. Jalal R, Goharshadi EK, Abareshi M, Moosavi M, Yousefi A, Nancarrow P. ZnO nanofluids: green synthesis, characterization, and antibacterial activity. Mater Chem Phys. 2010; 121(1): 198-201.
17. Moosavi M, Goharshadi EK, Youssefi A. Fabrication, characterization, and measurement of some physico- chemical properties of ZnO nanofluids. Int J Heat Fluid. 2010; 31(4): 599-605.
18. AshaRani P, Low Kah Mun G, Hande MP, Valiyaveettil S. Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano. 2008; 3(2): 279-290.
19. Nel A, Xia T, Mädler L, Li N. Toxic potential of materials at the nanolevel. Science. 2006; 311(5761): 622-627.
20. Xia T, Kovochich M, Liong M, Madler L, Gilbert B, Shi H. Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. ACS Nano. 2008; 2(10): 2121-2134.
21. Sharma V, Shukla RK, Saxena N, Parmar D, Das M, Dhawan A. DNA damaging potential of zinc oxide nanoparticles in human epidermal cells. Toxicol Lett. 2009; 185(3): 211-218.
22. Singh N, Manshian B, Jenkins GJ, Griffiths SM, Williams PM, Maffeis TG. NanoGenotoxicology: the DNA damaging potential of engineered nanomaterials. Biomaterials. 2009; 30(23): 3891-3914.
23. Xia T, Kovochich M, Brant J, Hotze M, Sempf J, Oberley T. Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Lett. 2006; 6(8): 1794-1807.