Clinical trials on silver nanoparticles for wound healing

Document Type : Review Paper


1 School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran

2 Department of Midwifery, Evidence-based Health Care Research Center, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran

3 Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran


Despite the prevalence of different kinds of wounds among people around the world, challenges ahead for managing wound healing continues. One of the most important issues for wound healing is infection that can delay healing process. Also, drug-resistant infections are growing as a worrying challenge in medicine. A lot of studies done over different methods to improve wound healing process, which in this regard, antibacterial nanoparticles have emerged to market for wound healing. Silver nanoparticles are the first kinds of nanoparticles that emerged in market as a wound dressing for wound healing and some of studies declared their clinical results for silver nanoparticles wound dressing for different kinds of wounds. In this review, we tried to browse clinical trials through using silver nanoparticles for wound healing to peruse the efficacy of silver nanoparticles dressing. The need for more study about efficacy and safety of silver nanoparticles is still a question.


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