Synthesis of CuO/Epoxy nanocomposites for the preparation of antifungal coating

Document Type: Research Paper

Authors

Department of Chemical Engineering, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran

Abstract

Objective(s): Antibacterial and antifungal nanocomposites are widely used in food packaging and pharmaceutical and medicine industries. Among the polymers of these nanocomposites, epoxy coatings are commonly used for health and industrial applications. The present study aimed to synthesize CuO nanoparticles using the chemical reduction method and characterized them by ultraviolet-visible (UV-Vis) spectroscopy and dynamic light scattering (DLS) analysis.
Materials and Methods: The nanoparticles were synthesized with the mean size of 45 nanometers. Following that, the CuO/epoxy nanocomposite were prepared in three concentrations of 1%, 3%, and 5% of the CuO nanoparticles. The results of X-ray diffractometry (XRD) and scanning electron microscopy (SEM) confirmed the presence of nanoparticles on the nanocomposite surface. In addition, the disc-diffusion method was used to assess the antifungal properties of the nanocomposites.
Results: The results of XRD and SEM confirmed the presence of CuO nanoparticles on the nanocomposite surface. The optimal nanocomposite concentration for the maximum antifungal activity was 3%.
Conclusion: It seems that the CuO nanoparticles could be used to provide antifungal nanocomposites, which are applicable in medicine and food industries.

Keywords


1.Sadeghnejad A, Aroujalian A, Raisi A, Fazel S. Antibacterial nano silver coating on the surface of polyethylene films using corona discharge, Surf. Coat Technol. 2014; 245: 1-8.
2.Ghorbani HR, Molaei M. Antibacterial nanocomposite preparation of polypropylene-Silver using Corona discharge, Prog. Organ Coat. 2017; 112: 187–190.
3.Ghorbani HR, Molaei M. Optimization of coating solution for preparation of antibacterial copper-polyethylene nanocomposite. Mater Res Express. 2017; 4: 065017.
4. Kim JS, Kuk E, Yu KN, Kim JH, Park SJ, Lee HJ, Kim SH, Park YK, Park YH, Hwang CY, Kim YK, Lee YS, Jeong DH, Cho MH. Antimicrobial effects of silver nanoparticles, Nanomed nanotech boil med. 2007; 3: 95–101.
5. Ojeda M, Kumar DK, Chen B, Xuan J, Maorto-Valer MM, Leung DYC, Wang H. Polymeric templating synthesis of Anatase TiO2 nanoparticles from low-cost inorganic titanium sources. Chem Select. 2017; 2: 702–706.
6. Phu DV, Quoc LA, Duy NN, Lan NTK, B. Du D, Luan LQ, Hien NQ, Study on antibacterial activity of silver nanoparticles synthesized by gamma irradiation method using different stabilizers. Nanoscale Res Lett. 2014; 9: 162-167.
7. Moosa AA, Ramazani A, Ibrahim MN. Effects of Carbon Nanotubes on the Mechanical and Electrical Properties of Epoxy Nanocomposites. Inter J Curr Eng Technol. 2015; 5: 3253-3258.
8. Fayomi OSI, Popoola OPI. Anti-corrosion properties and structural characteristics of fabricated ternary coatings, Surf Eng App Electrochem. 2015; 51: 76–84.
9. Ghorbani HR, Alizadeh V, Parsa Mehr F, Jafarpour golroudbary H, Erfan K, Sadeghi Yeganeh S. Preparation of polyurethane/CuO coating film and the study of antifungal activity, Prog Organ Coat. 2018; 123:322–325.
10. Ghorbani HR. Biological and non-biological methods for fabrication of copper nanoparticles, Chem Eng Commun. 2015; 202: 1463-1467.
11. Kaszuba M, McKnight D, Connah MT, McNeil-Watson FK, Nobbmann U. Measuring sub nanometre sizes using dynamic light scattering. J Nanopart Res. 2008; 10: 823-829.
12. Chandra S, Kumar A, Tomar PK. Synthesis and characterization of copper nanoparticles by reducing agent. J Saudi Chem Soc. 2014; 18: 149–153.
13. Doodi M, Naghsh N, Heidarpour A. Effect of silver nanoparticles on pathogenic Gram-negative bacilli resistant to extended spectrum beta-lactamase (ESBLs) antibiotics. Lab J. 2011; 5(2): 44-51.
14. Monsef Khosh-hesab Z. Synthesis of ZnO nanoparticles using chemical deposition method. Int Nano Lett. 2011; 1(4): 39-49.
15. Naghsh N, Safari M, Haj Mehrabi P. Effect of silver nanoparticles on E. coli growth. J Qom Univ Med Sci. 2011; 6(2): 65-68.
16. Veissi Malekshahi Z, Afshar D, Ranjbar R, Shirazi MH, Rezaei F, Mahboobi R, and colleagues. Antimicrobial properties of ZnO nanoparticles. J MDPI Tropical Med. 2012; 17(59): 1-4.
17. Soo-Hwan K, Lee HS, Ryo DS, Choi SJ, Lee DS. Antibacterial Activity of Silver-nanoparticles Against Staphylococcus aureus and Escherichia coli. Korean J Microbiol Biotechnol. 2011; 39(1): 77-85.
18. Zhang YC, Tang JY, Wang GL, Zhang M, Hu XY. Facile synthesis of submicron Cu2O and CuO crystallites from a solid metallorganic molecular precursor. J Crys Growth. 2006; 294(2): 278-282.
19. Yoon K, Hoon Byeon J, Park JH, Hwang J. Susceptibility constants of Escherichia coli and Bacillus subtilis to silver and copper nanoparticles. Sci Total Environ. 2007; 373(2-3): 572-575.
20. Ruparelia JP, Chatterjee AK, Duttagupta SP, Mukherji S. Strain specificity in antimicrobial activity of silver and copper nanoparticles. Acta Biomater. 2008; 4(3): 707-716.
21. Singh R, Shedbalkar UU, Wadhwani SA, Chopade BA. Bacteriagenic silver nanoparticles: synthesis, mechanism, and applications. Appl Microbiol Biotechnol. 2015; 99(11): 4579–4593.
22. Hosseini-Abari A, Emtiazi G, Lee SH, Kim BG, Kim JH. Biosynthesis of silver nanoparticles by Bacillus stratosphericus spores and the role of dipicolinic acid in this process. Appl Biochem Biotechno. 2014; 174(1): 270-282
23. Wei Y, Chen S, Kowalczyk B, Huda S, Gray TP, Grzybowski BA. Synthesis of stable, low-dispersity copper nanoparticles and nanorods and their antifungal and catalytic properties. J Phys Chem C. 2010; 114: 15612–15616.
24. Shao W, Wang S, Wu J, Huang M, Liu H, Min H. Synthesis and antimicrobial activity of copper nanoparticle loaded regenerated bacterial cellulose membranes, RSC Adv. 2016; 6: 65879-65884.
25. Ramyadevi J, Jeyasubramanian K, Marikani A, Rajakumar G, Rahuman AA. Synthesis and antimicrobial activity of copper nanoparticles. Mater Lett. 2012; 71: 114–116.